Thank you for visiting our website. Our laboratories are situated in the BioScience Research Collaborative (BRC) Building at Rice University in the space-age city of Houston, Texas. Our research is focused on the chemistry, biology, and medicine of natural and designed molecules.

The structures below this text represent some of the most intriguing naturally occurring molecules synthesized in our laboratories in recent years. More can be found in the accomplishments section and in the publications listed. In addition to research, we are deeply committed to the education and training of a new generation of men and women in the chemical sciences.

The group has published several instructive books, including the advanced and widely used textbooks Classics in Total Synthesis (K. C. Nicolaou and Erik J. Sorensen, VCH, 1996), Classics in Total Synthesis II (K. C. Nicolaou and Scott A. Snyder, Wiley-VCH, 2003), Molecules That Changed the World (K. C. Nicolaou and T. Montagnon, Wiley-VCH, 2008), and Classics in Total Synthesis III (K. C. Nicolaou and J. S. Chen, Wiley-VCH, 2011). Enjoy the tour of our world.