Earth Human STR Allele Frequencies Database

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Earth Human STR Allele Frequencies Database
Type of site
Population Genetics Project
Available inEnglish
Headquarters
Romania
Created byStanciu Florin
URLwww.ehstrafd.org
RegistrationOptional
Launched1 January 2009
Current statusInactive

The Earth Human STR Allele Frequencies Database[1] is a scientific project based on a dynamic web interface and a relational database management system. Its main purpose is the management of STR populational data reported from all over the world, providing highly specialized population genetics tools and also an overview of world population genetic structure at global scale.

At the bottom of EHSTRAFD approach stays peer-review journals standardization trend in publishing populational data[2] and most important, the allele frequencies gradient distribution over vast geographical areas.[3][4][5]

Database Tools (Modules)

Allele Frequency Global Tracking (AFGT) - allows searching for allele frequency distribution at global and regional level. STR Loci are available in AFGT if there are reported in at least ten EHSTRAFD populations. The AFGT locus list is permanently updated with each EHSTRAFD release.

Regional Profile Frequency (RPF) - allows calculating the frequency of a genetic profile at global and regional level, base on EHSTRAFD current records. RPF is available just for ISSOL (Interpol Standard Set Of Loci), ESS (European Standard Set - recommended by ENFSI) and CODIS (Combined DNA Index System) loci.

Most Probable Geographical Origin (MPGO) - allows searching for the most probable geographical origin of a given STR genetic profile. Geographical origin is estimated by the profile frequency in different populations. MPGO is available just for ISSOL (Interpol Standard Set Of Loci), ESS (European Standard Set - recommended by ENFSI) and CODIS (Combined DNA Index System) loci.

See also

References

  1. ^ EHSTRAFD - Earth Human STR Allele Frequencies Database. c2009 [cited on 14 Jun 2009 - R1]. Available from http://www.ehstrafd.org Archived 2009-07-13 at the Wayback Machine
  2. ^ Patrick Lincoln, Angel Carracedo. Publication of population data of human polymorphisms. Forensic Sci Int. 2000;110(1):3-5.
  3. ^ Yates GB. Gradient Correlation Theory. c1996 [citat la 16 Mai 2009] . Disponibila de la http://www.autismtheory.org/GradientCorrelation.htm Archived 2009-06-25 at the Wayback Machine
  4. ^ Serre D, Pääbo S. Evidence for gradients of human genetic diversity within and among continents. Genome Res. 2004;14(9):1679-85.
  5. ^ Roewer L, Croucher PJ, Willuweit S, Lu TT, Kayser M, Lessig R, de Knijff P, Jobling MA, Tyler-Smith C, Krawczak M. Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Hum Genet. 2005;116(4):279-91
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