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Link to original content: http://glycosmos.org/genes/9331
GlyCosmos Portal
beta-1,4-galactosyltransferase 6

Summary
Gene Symbol
  • B4GALT6
Aliases
  • UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase
  • beta4GalT-VI
Organism
Homo sapiens (human)
External Links
NCBI Gene
9331
GGDB ID
HGNC
929
mRNA
map
  • 18q11
Protein
OMIM
KEGG Gene ID
hsa:9331
PubChem
9331
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Calcium
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid biosynthesis
  • Magnesium
  • Manganese
  • Metal-binding
  • Proteomics identification
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transmembrane helix
Proteins
Displaying all 4 entries
UniProt Protein Name
Q59GB5
Q9UBX8
  • Glucosylceramide beta-1,4-galactosyltransferase
  • Lactosylceramide synthase
  • UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6
  • UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase
  • UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6
Q8WZ95
G3XA83
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000118276

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

GlycoGene Database (GGDB)
GGDB ID
gg082
Gene Symbol
  • B4GALT6
Reactions
Displaying 1 entry
Donor Acceptor Product Reference
UDP-Gal
G71142DF
G84224TW
Displaying 1 entry
Donor Acceptor Product Reference
UDP-Gal
G71142DF
G84224TW
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Rattus norvegicus NP_113928 NM_031740
Mus musculus NP_062711 NM_019737
KEGG BRITE Database
Orthology
K07553
Name
beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06276
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0080199 colorectal carcinoma
DOID:2377 multiple sclerosis
DOID:37 skin disease
DOID:5672 large intestine cancer
DOID:9256 colorectal cancer
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP000039
Gene Name
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024