Mannosylglycoprotein endo-beta-mannosidase
(Redirected from Mannosylglycoprotein endo-b-mannosidase)
| Mannosylglycoprotein endo-beta-mannosidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.2.1.152 | ||||||||
| CAS no. | 141176-95-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Mannosylglycoprotein endo-beta-mannosidase (EC 3.2.1.152, endo-beta-mannosidase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction:
- Hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl sequences
The substrate group is a substituent on N-4 of an asparagine residue in the glycoprotein.
References
[edit]- ^ Ishimizu T, Sasaki A, Okutani S, Maeda M, Yamagishi M, Hase S (September 2004). "Endo-beta-mannosidase, a plant enzyme acting on N-glycan: purification, molecular cloning, and characterization". The Journal of Biological Chemistry. 279 (37): 38555–62. doi:10.1074/jbc.m406886200. PMID 15247239.
- ^ Sasaki A, Yamagishi M, Mega T, Norioka S, Natsuka S, Hase S (February 1999). "Partial purification and characterization of a novel endo-beta-mannosidase acting on N-linked sugar chains from Lilium longflorum thumb". Journal of Biochemistry. 125 (2): 363–7. doi:10.1093/oxfordjournals.jbchem.a022295. PMID 9990135.
External links
[edit]- Mannosylglycoprotein+endo-beta-mannosidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
