Antiandrogen | Relative potency |
---|---|
Bicalutamide | 4.3 |
Hydroxyflutamide | 3.5 |
Flutamide | 3.3 |
Cyproterone acetate | 1.0 |
Zanoterone | 0.4 |
Description: Relative potencies of orally administered antiandrogens in antagonizing 0.8 to 1.0 mg/kg s.c. testosterone propionate-induced ventral prostate weight increase in castrated immature male rats. Higher values mean greater potency. Sources: [1] |
References
edit- ^ Snyder BW, Winneker RC, Batzold FH (December 1989). "Endocrine profile of Win 49596 in the rat: a novel androgen receptor antagonist". J. Steroid Biochem. 33 (6): 1127–32. doi:10.1016/0022-4731(89)90419-6. PMID 2615357.